We explored the effects of all-trans retinoic acid (atRA) on atherosclerosis in rabbits fed a high-fat diet. In an experiment where rabbits were divided into groups, some received atRA while others received atorvastatin or both.
We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.
Read More
9
Vitamin A may help cholesterol levels
Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain.
We examined the effects of a vitamin A-enriched diet on cholesterol levels in glucose-intolerant obese rats. Over a 14-week period, we fed two groups of rats—one received a standard diet, while the other enjoyed the vitamin A boost.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
Read More
8
Vitamin A lowers cholesterol in rats
Vitamin A-enriched diet modulates reverse cholesterol transport in hypercholesterolemic obese rats of the WNIN/Ob strain.
We explored how vitamin A affects cholesterol levels in obese rats with high cholesterol. By administering different doses of vitamin A, we found that a dose of 52 mg/kg significantly decreased the unhealthy HDL-cholesterol levels after 20 weeks. This feeding regimen increased the expression of proteins that help with cholesterol transport. However, the lean rats didn’t show similar benefits. The findings suggest that vitamin A might offer a way to improve cholesterol metabolism in obese individuals, but more research is needed before making any human recommendations.
Read More
Most Useful Reviews
9
Health improvements
90 people found this helpful
Excellent! After taking this vitamin for a month before my doctor’s checkup, she was amazed at my health improvements—my cholesterol levels, blood pressure, and energy levels are all normal now. I feel significantly more energised!
Read More
6
Promotes hair health
3 people found this helpful
The hairdresser recommended this for hair loss. It truly helps by giving shine and thickness to my hair while also reducing cholesterol levels.
Read More
9
Skin improvement
1 people found this helpful
I purchased this drug for its high dosage. Within a week, my hand skin became very smooth—a result I struggled to achieve during winter and spring. After taking the vitamin, the outcome is simply perfect. Highly recommend it!
We explored the effects of all-trans retinoic acid (atRA) on atherosclerosis in rabbits fed a high-fat diet. In an experiment where rabbits were divided into groups, some received atRA while others received atorvastatin or both.
We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.
Read More
9
Vitamin A may help cholesterol levels
Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain.
We examined the effects of a vitamin A-enriched diet on cholesterol levels in glucose-intolerant obese rats. Over a 14-week period, we fed two groups of rats—one received a standard diet, while the other enjoyed the vitamin A boost.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
Read More
8
Vitamin A lowers cholesterol in rats
Vitamin A-enriched diet modulates reverse cholesterol transport in hypercholesterolemic obese rats of the WNIN/Ob strain.
We explored how vitamin A affects cholesterol levels in obese rats with high cholesterol. By administering different doses of vitamin A, we found that a dose of 52 mg/kg significantly decreased the unhealthy HDL-cholesterol levels after 20 weeks. This feeding regimen increased the expression of proteins that help with cholesterol transport. However, the lean rats didn’t show similar benefits. The findings suggest that vitamin A might offer a way to improve cholesterol metabolism in obese individuals, but more research is needed before making any human recommendations.
Read More
7
Vitamin A helps improve cholesterol
THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION.
We investigated how antioxidant therapy, including vitamins A and E, affects patients with non-alcoholic steatohepatitis (NASH) who were involved in the Chernobyl disaster.
By studying 72 patients through blood tests and ultrasounds before and after treatment, we found that this combined treatment improved antioxidant levels in the body.
It also resulted in lower cholesterol levels and better liver health overall. Thus, vitamin A therapy showed promise in managing cholesterol and other metabolic issues in these patients.
Read More
4
Vitamin A shows limited cholesterol effects
A comparative study of antioxidant vitamins and simvastatin in hypercholesterolimic rabbits.
We explored how antioxidant vitamins, particularly vitamin A, vitamin C, and vitamin E, impact cholesterol levels in rabbits fed high cholesterol diets.
In our research, we noted that while all treatment groups saw a reduction in total cholesterol and triglycerides, vitamin A did not perform as well as vitamin C, vitamin E, or simvastatin.
Ultimately, simvastatin stood out for significantly increasing beneficial HDL-C levels, while vitamin A showed limited effectiveness in comparison.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.3
All Reviews
Positive Reviews
Negative Reviews
9
Health improvements
90 people found this helpful
Excellent! After taking this vitamin for a month before my doctor’s checkup, she was amazed at my health improvements—my cholesterol levels, blood pressure, and energy levels are all normal now. I feel significantly more energised!
Read More
6
Promotes hair health
3 people found this helpful
The hairdresser recommended this for hair loss. It truly helps by giving shine and thickness to my hair while also reducing cholesterol levels.
Read More
9
Skin improvement
1 people found this helpful
I purchased this drug for its high dosage. Within a week, my hand skin became very smooth—a result I struggled to achieve during winter and spring. After taking the vitamin, the outcome is simply perfect. Highly recommend it!
Read More
9
Effective cholesterol treatment
222 people found this helpful
I liked the vitamin; the quality is excellent with superb ingredients. I experienced the expected effect from its use, and the size is favourable. The effect is noticeable after a week, and I truly like it! I recommend buying it.
Read More
7
Preventive care
14 people found this helpful
Effective for dry eyes! I take 10,000 units daily and find that while it's needed in small amounts, if excess is taken, it can create issues. People with gastric ulcers or cancer in the family must be careful, even at the maximum dose. A high-protein diet is important to accompany this.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Vitamin A is a fat-soluble vitamin that's essential for several critical bodily functions, including vision, immune response, and cell differentiation. It comes in two primary forms: preformed vitamin A (retinol) found in animal products like liver, fish, and dairy, and provitamin A carotenoids, primarily found in colorful fruits and vegetables such as carrots, sweet potatoes, and spinach. The body can convert carotenoids into retinol, making these plant sources a valuable dietary option, especially for those following a vegetarian or vegan lifestyle.
Aside from its role in maintaining healthy vision—particularly in low-light conditions—vitamin A plays a significant role in skin health and the functioning of the heart, lungs, and kidneys. It also supports the immune system by promoting the development and function of white blood cells. While it's uncommon to experience a deficiency in countries where a balanced diet is accessible, a lack of vitamin A can lead to serious health problems, including night blindness and increased susceptibility to infections. In contrast, excessive intake of vitamin A, particularly through supplements, can be toxic and lead to several health issues, making it crucial to maintain a balanced intake.
According to user reviews, the time it typically takes to see results from the supplement for high cholesterol can vary. Some users report noticeable improvements within as little as one week. For instance, one reviewer mentioned experiencing significant health improvements, including normal cholesterol levels, within a month of taking the supplement before a doctor's checkup Read Review. In another review, a user highlighted the immediate effects within just a week, emphasizing the overall expected effects from the vitamin Read Review.
While individual experiences may vary, several users express satisfaction with the results they’ve observed in a relatively short time frame, suggesting a range of effectiveness that can be appraised within weeks. However, it’s essential to consult your healthcare provider for tailored advice and to set realistic expectations based on your unique health needs and circumstances.
Recent research indicates that vitamin A may have potential benefits for managing high cholesterol levels, though the effectiveness varies based on individual characteristics and study methodologies. For instance, one study found that vitamin A significantly reduced cholesterol levels in patients with non-alcoholic fatty liver disease, suggesting its role in improving lipid profiles [1]. Additionally, animal studies highlighted vitamin A's ability to lower cholesterol in obese rats and improve serum lipid profiles, indicating a promising avenue for managing cholesterol levels [3].
However, it's important to bear in mind that not all studies show vitamin A as equally effective compared to established treatments. For example, while a study showed a reduction in cholesterol among rabbits given vitamin A, the results were not as significant as those seen with other antioxidants or cholesterol-lowering medications like atorvastatin [5]. Overall, while certain studies support the idea that vitamin A may help in cholesterol management, further research, particularly in human subjects, is warranted before widespread recommendations can be made.
Based on user reviews, many individuals have reported a variety of improvements in their symptoms after taking the vitamin. A notable example is from a user who experienced remarkable health enhancements, including normalized cholesterol levels, improved blood pressure, and increased energy after just one month of use Read Review. For those focused on skin health, another reviewer mentioned that their skin became significantly smoother within a week, a change they struggled to achieve previously Read Review. Users have also reported benefits such as reduced acne, better skin hydration, and even improved eyesight Read ReviewRead Review.
Moreover, some have specifically targeted hair wellness with increases in shine and thickness being mentioned alongside reductions in cholesterol levels Read Review. It's vital to keep in mind that individual experiences can differ, and factors such as underlying health conditions and dosage can influence results. As always, consulting with a healthcare provider is recommended to tailor any supplement use to your personal health needs.
Users have reported mixed experiences when combining this supplement for high cholesterol with other supplements. For instance, one reviewer highlighted a positive synergy between this vitamin and neem capsules, noting significant improvements in skin quality after using both together Read Review. This combination seemed to effectively target skin issues, particularly after undergoing treatments like Roaccutane. Conversely, another user cautioned that this vitamin might deplete other nutrients and cautioned those with asthma or low iron to proceed with caution, as higher doses could exacerbate breathing issues Read Review.
While the anecdotal evidence suggests some users find success in stacking this vitamin with others, it is essential to have a careful approach, especially considering potential interactions or nutrient depletion effects. Hence, individuals may want to consult healthcare professionals before starting any new supplement regimen that includes this vitamin alongside others.
Based on user reviews, there seems to be a significant variation in the reported dosages of Vitamin A used for managing high cholesterol. Some users have found that taking around 10,000 units daily has benefitted their overall health, including cholesterol levels, while others indicate a preference for lower doses due to concerns about potential side effects. For instance, one user noted they experienced a spike in cholesterol levels after switching to a product with added oils and recommended caution for those with pre-existing conditions such as asthma or low iron Read Review. Another user cautioned about the risks of higher doses, suggesting that Vitamin A can deplete other nutrients and is best taken intermittently Read Review.
User experiences highlight that while some individuals had success with vitamin A in improving their cholesterol levels, they also noted the importance of accompanying a high-protein diet and balancing other nutrient intake. For many, the desired improvements were noticeable after a few weeks, reinforcing the idea that the right dose can vary significantly among individuals and that users should consult healthcare professionals to determine what works best for their specific health needs Read Review.
9
Health improvements
90 people found this helpful
Excellent! After taking this vitamin for a month before my doctor’s checkup, she was amazed at my health improvements—my cholesterol levels, blood pressure, and energy levels are all normal now. I feel significantly more energised!
9
Effective cholesterol treatment
222 people found this helpful
I liked the vitamin; the quality is excellent with superb ingredients. I experienced the expected effect from its use, and the size is favourable. The effect is noticeable after a week, and I truly like it! I recommend buying it.
9
Skin improvement
1 people found this helpful
I purchased this drug for its high dosage. Within a week, my hand skin became very smooth—a result I struggled to achieve during winter and spring. After taking the vitamin, the outcome is simply perfect. Highly recommend it!
7.5
Improves eyesight
7 people found this helpful
Excellent vitamin A supplement. I use it occasionally for my eyesight, as it strengthens vision, particularly for glasses wearers. I noticed an improvement, especially in my skin; spots vanished and my cheeks’ pinkness reduced. The small package lasts three months at one pill a day. Overall, vitamin A is exceptional for hair, skin, and eyesight. This company's product quality is high.
9
Notable improvements
2 people found this helpful
Excellent! I take this vitamin every morning after acne treatment and antibiotics, alongside vitamins C and E. I see results and believe it's working. The product quality is high and reasonably priced. My skin has greatly improved after months of treatment for acne.
6
Promotes hair health
3 people found this helpful
The hairdresser recommended this for hair loss. It truly helps by giving shine and thickness to my hair while also reducing cholesterol levels.
7.5
Quick skin improvement
1 people found this helpful
I've been taking this supplement with neem capsules and am thrilled with the improvement in my skin. Roaccutane contains high doses of vitamin A, leading me to this supplement. It's working well for me—my skin clears up quickly after breakouts.
0
Use with caution
125 people found this helpful
CAUTION FOR ASTHMA / LOW IRON - this vitamin A can deplete other nutrients and may cause asthma. Higher doses could be detrimental for those low in iron or asthmatics. I advise occasional use only, as it can make me breathless, requiring supplementation of other nutrients. A natural vitamin A in lower doses seems impossible to find, especially one that isn't cod. If this review helped, please click YES below - thank you.
1
Concerns about oils
1 people found this helpful
I am vegan and oil-free, but after taking these vitamins, my cholesterol levels sky-rocketed. I’ve never had problems before; now I see safflower oil, palm oil, and olive oil are added. Why is this?
7
Vitamin A helps improve cholesterol
THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION.
We investigated how antioxidant therapy, including vitamins A and E, affects patients with non-alcoholic steatohepatitis (NASH) who were involved in the Chernobyl disaster.
By studying 72 patients through blood tests and ultrasounds before and after treatment, we found that this combined treatment improved antioxidant levels in the body.
It also resulted in lower cholesterol levels and better liver health overall. Thus, vitamin A therapy showed promise in managing cholesterol and other metabolic issues in these patients.
9
Vitamin A may help cholesterol levels
Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain.
We examined the effects of a vitamin A-enriched diet on cholesterol levels in glucose-intolerant obese rats. Over a 14-week period, we fed two groups of rats—one received a standard diet, while the other enjoyed the vitamin A boost.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
4
Vitamin A shows limited cholesterol effects
A comparative study of antioxidant vitamins and simvastatin in hypercholesterolimic rabbits.
We explored how antioxidant vitamins, particularly vitamin A, vitamin C, and vitamin E, impact cholesterol levels in rabbits fed high cholesterol diets.
In our research, we noted that while all treatment groups saw a reduction in total cholesterol and triglycerides, vitamin A did not perform as well as vitamin C, vitamin E, or simvastatin.
Ultimately, simvastatin stood out for significantly increasing beneficial HDL-C levels, while vitamin A showed limited effectiveness in comparison.
References
Sarkisova EA, Chumak AA, Ovsyannikova LM, Alekhina LM, Nosach OV, et al. THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION. Probl Radiac Med Radiobiol. 2018;23:452. doi:10.33145/2304-8336-2018-23-452-461
Zarei L, Bahrami M, Farhad N, Froushani SMA, Abbasi A. All-trans retinoic acid effectively reduces atheroma plaque size in a rabbit model of high-fat-induced atherosclerosis. Adv Clin Exp Med. 2018;27:1631. doi:10.17219/acem/74552
Jeyakumar SM, Sheril A, Vajreswari A. Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain. Indian J Med Res. 2016;144:238. doi:10.4103/0971-5916.195038
Prashanth A, Jeyakumar SM, Giridharan NV, Vajreswari A. Vitamin A-enriched diet modulates reverse cholesterol transport in hypercholesterolemic obese rats of the WNIN/Ob strain. J Atheroscler Thromb. 2014;21:1197.
Syed NI, Arshad S, Syed AA, Ahmad M, Khan FZ, et al. A comparative study of antioxidant vitamins and simvastatin in hypercholesterolimic rabbits. Pak J Pharm Sci. 2011;24:479.